André Fabio Kohn,
Ph.D.
andfkohn@leb.usp.br
phone: (55-11) 3091-5535 fax: (55-11) 3091-5718
E.E.(Electrical Engineering):
Universidade de São Paulo (USP), Escola Politécnica, Dec. 1973 M.S.E.E. : Universidade de São Paulo
(USP), 1976 (research on computerized electrocochleography) Ph.D. : University of California at Los
Angeles (UCLA), 1980 (research on the communication across an
inhibitory synapse in crayfish and in eletronic and
mathematical models) Professor of Biomedical Engineering at
USP Founder and co-Director of the
Biomedical Engineering Laboratory at USP Member of the campus-wide Neuroscience
graduate program at USP Researcher at the National
Institutes of Health (NINDS) from 10/1994 to 4/1995 Research Interests Human Neurophysiology
with Emphasis on the Spinal Cord Modeling and Simulation
of Neurons and Neuronal Networks Motor Control in Humans
and Animals Clinical Neurophysiology Biomedical Signal Processing
and Pattern Recognition
MS and Ph.D. advisor
I advise students from engineering, physics, computer science and equivalent backgrounds in the Electrical Engineering Program of the Escola Politécnica
da USP (http://www.pcs.usp.br/~posgrad-eletrica/). These students usually do research on the mathematical modelling of neurons and their networks, synapses, muscles and the
complex interactions of all these elements together. One of the goals is to increase knowledge related to motor control at different levels of organization. I also advise
students from biomedical sciences backgrounds in the
campus-wide Neurosciences Program (http://www.ip.usp.br/portal/index.php?option=com_content&view=article&id=949%3Aapresentacao-do-programa-de-pos-graduacao-em-neurociencias-e-comportamento&catid=252&Itemid=114&lang=pt). These
students do experimental work dealing with human motor
control and human spinal cord. Papers
and Book Chapters R.A.
Mezzarane, L.A.
Elias, F.H. Magalhães,
V.M Chaud
and A.F. Kohn (2013).
Experimental
and Simulated EMG Responses in the Study of the Human
Spinal Cord "Electrodiagnosis in New
Frontiers of Clinical Research", book
edited by Hande Turker, ISBN 978-953-51-1118-4,
Published: May 22, 2013 under CC BY 3.0 license F.H. Magalhães,
D.R. Toledo and A.F. Kohn (2013).
Plantar
flexion force induced by amplitude-modulated tendon
vibration and associated soleus V/F-waves as an
evidence of a centrally-mediated mechanism
contributing to extra torque generation in
humans Journal
of NeuroEngineering and Rehabilitation 2013,
10:32 L.A. Elias and A.F.
Kohn (2013).
Individual and collective
properties of computationally efficient
motoneuron models of types S and F with active
dendrites Neurocomputing
- Volume 99, 1 January 2013, Pages 521–533 R. A. Mezzarane, A. F. Kohn, E. Couto-Roldan, L.
Martinez, A. Flores and E. Majarrez (2012)
Absence
of effects of contralateral group I muscle afferents
on presynaptic inhibition of Ia terminals in humans
and cats Journal
of Neurophysiology August
15, 2012 vol. 108 no. 4
1176-1185 L.A. Elias, V.M
Chaud and A.F. Kohn (2012).
Models of passive and active
dendrite motoneuron pools and their differences
in muscle force control Journal of Computational Neuroscience,
December 2012, Volume 33, Issue 3, pp 515-531. F.H. Magalhães
and A.F. Kohn (2012).
Imperceptible
electrical noise attenuates isometric plantar
flexion force fluctuations with correlated
reductions in postural sway. Experimental Brain Research 2012
Mar;217(2):175-186. Epub 2011 Dec 24. F.H. Magalhães
and A.F. Kohn (2011).
Vibratory
noise
to the fingertip enhances balance improvement
associated with light touch. Experimental Brain Research 209,
139-151. F.H. Magalhães
and A.F. Kohn (2011).
Vibration-enhanced
posture
stabilization
achieved by tactile supplementation: May blind
individuals get extra benefits? Medical Hypotheses. 2011 May 20.
P. H. Marchetti,
A. F. Kohn and M. Duarte (2011).
Selective
activation of the rectus abdominis muscle during
low-intensity and fatiguing tasks. Journal of Sports Science
and Medicine(2011)
10, 322-327. F.H. Magalhães and A.F. Kohn (2010).
Vibration-induced
extra
torque
during
electrically-evoked
contractions
of
the
human
calf muscles. Journal Neuroengineering and
Rehabilitation, 7:26 R. A. Mezzarane and A. F. Kohn (2009)
A
method to estimate EMG crosstalk between two muscles
based on the silent period following an H-reflex.
Medical Engineering & Physics 31 (2009) 1331-1336 R. A. Mezzarane and A. F. Kohn (2008)
Postural
control during kneeling. Experimental Brain Research (2008)
187:395–405. DOI 10.1007/s00221-008-1308-x M.C.S. Fornari and A.F. Kohn (2008).
High
frequency
tendon reflexes in the human soleus muscle.
Neuroscience Letters, v. 440, p. 193-196. DOI
10.1016/j.neulet.2008.05.075. R.R.L. Cisi and A.F. Kohn (2008).
Simulation
system of spinal cord motor nuclei and associated
nerves and muscles, in a web-based architecture.
Journal of Computational Neuroscience, 25, 520-542.
DOI 10.1007/s10827-008-0092-8. R.A. Mezzarane and A.F. Kohn (2007).
Control
of upright stance over inclined surfaces.
Experimental Brain Research, 180, 377-388. M.F. Vieira and A.F. Kohn (2007).
Compartmental
models
of
mammalian
motoneurons of types S, FR and FF and their computer
simulation . Computers in Biology and Medicine,
37, 842-860. A.F. Kohn(2006).
Autocorrelation and Cross-correlation Methods
. Wiley Encyclopedia of Biomedical Engineering,
Ed. Metin Akay. New Jersey: John Wiley & Sons, 23
pp. A.F. Kohn (2005).
Cross-correlation
between
EMG
and
center
of
gravity
during
quiet
stance: theory and simulations. Biological Cybernetics, 93, 382-388. E. Manjarrez, Z. Hernández-Paxtián and A.F. Kohn
(2005).
Spinal
source
for
the
synchronous
fluctuations
of
bilateral
monosynaptic
reflexes
in cats. Journal of Neurophysiology, 94,
3199-3210.
L.M. Lucchesi, S. Pompéia, G.M. Manzano, A.F.
Kohn, J.C. Galduroz, O.F.A. Bueno and S. Tufik (2003).
Flunitrazepam-induced
changes
in
neurophysiological,
behavioural
and
subjective
measures
used
to
assess
sedation. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 27, 525-533. A.F. Kohn e M.F. Vieira (2002).
Optimality
in
the
encoding/decoding
relations
of
motoneurones
and
muscle
units. Biosystems, 67, 113-119. R.A. Mezzarane and A.F. Kohn (2002).
Bilateral
soleus
H-reflexes
in
humans
elicited
by
simultaneous
trains
of stimuli: symmetry, variability and covariance.
Journal of Neurophysiology, 87, 2074-2083. G.M. Manzano and A.F. Kohn (2000).
Proximal
receptors
and
the
mechanical stimulation of the fingers: a
somatosensory evoked potential study.
Electromyography and Clinical
Neurophysiology, 40, 21-29. D.G. Goroso, R.R.L. Cisi and A.F. Kohn (2000).
The amplitude
and phase responses of the firing rates of some
motoneuron models. Biosystems, 58, 33-39. A. F. Kohn (1998).
Effects
of
synaptic
noise on a neuronal pool model with strong
excitatory drive and recurrent inhibition.
Biosystems, 48, 113-121. A.F. Kohn, M.K. Floeter and M. Hallett (1997).
Presynaptic
inhibition
compared
with
homosynaptic
depression
as
an
explanation for soleus H reflex depression in humans.
Experimental Brain Research, 116, 375-380. M. K. Floeter and A. F. Kohn (1997).
H
reflexes of different sizes exhibit differential
sensitivity to low frequency depression.
Electroencephalography and Clinical Neurophysiology (Electromyography
and motor control), 105, 470-475. A. F. Kohn (1997).
Computer
simulations
of
noise
resulting
from
random
synaptic activities. Computers in Biology and Medicine, 27,
293-308. A.F. Kohn, L.G.M. Nakano, M. Oliveira and Silva
(1996).
A
class discriminability measure based on feature
space partitioning. Pattern Recognition, 29,
873-887. A.F. Kohn and S. S. Furuie (1991).
Safety
in medical signal analysis. Engineering in Medicine and Biology Magazine, IEEE, 10, pages 56 and 62. A.F. Kohn (1989).
A
versatile waveform generator for testing
neuroeletric signal processors. Journal of Neuroscience Methods, 29, 157-163. A.F. Kohn (1989).
Dendritic
transformations
on random synaptic inputs as measured from a
neuron's spike train - Modeling and simulation.
IEEE Transactions on Biomedical Engineering, 36, 44-54. A.F. Kohn (1987).
Phase
distortion
in biological signal analysis caused by linear phase
FIR filters. Medical & Biological Engineering & Computing, 25, 231-238. O.D.Martinez, A.F.Kohn and J.P.Segundo (1983).
Pervasive
locking,
saturation,
asymmetric
rate
sensitivity
and double- valuedness in crayfish strech-receptors.
Biological Cybernetics, 49, 33-45. A.F.Kohn and J.P.Segundo (1983).
Neuromime
and computer simulations of synaptic interactions
between pacemakers. Mathematical expansions of
existing models. Journal of Theoretical Neurobiology., 2,
101-125. A.F.Kohn, A.F.Rocha and J.P.Segundo (1981).
Presynaptic
irregularity and pacemaker inhibition. Biological Cybernetics, 41, 5-18. J.P.Segundo and A.F.Kohn (1981).
A
model of excitatory synaptic interactions between
pacemakers. Its reality, its generality and the
principles involved. Biological Cybernetics, 40, 113-126.
Selected
Conference Publications R.R.L. Cisi and A.F. Kohn (2008). From
neuronal ionic channels to muscle control: a Web-based
simulator and its application to teaching. World
Congress of Engineering /International Conference on
Systems Biology and Bioengineering. London, pp 1-4. A.F. Kohn (2007).
Estimation
of neural noise spectrum in a postural control model.
IFMBE Proceedings, vol. 16, of the 11th Mediterranean
Conference on Medical and Biological Engineering
(Ljubljana, Slovenia), 419-422. L.A. Okai e A.F. Kohn (2006). The influence of the
flexor digitorum brevis muscle on postural stability. XVI
Congress of the International Society of Electrophysiology
and Kinesiology (Torino, Italy), pp 1. R.R.L.Cisi and A.F. Kohn (2004).
Spinal
Cord Neuronal Network Simulator. Proceedings of the
28th Conference of the Canadian Medical and Biological
Engineering Society (Quebec, Canadá), CD-ROM, pp 1-3. A.F. Kohn, M. K. Floeter and M. Hallett (1995).
A
model-based approach for the quantification of H reflex
depression in humans. 17th Annual International
Conference of the IEEE Engineering in Medicine and Biology
Society (Montreal, Canada). Spinal cord neurophysiology
studied by means of the analysis of postural and
reflex dynamics. Analysis of the electrical activity of
muscles, nerves and the brain for research and clinical
diagnosis. Mathematical modeling and simulation of
neurons, synapses and neuronal networks of the spinal
cord. Some
Activities at the University of Sao Paulo Teaching undergraduate and
graduate courses, e.g., Signals and Systems I and
II, Fundamentals of Neuroscience, Spinal Cord
Neurophysiology, Neurophysiology of Motor Control, Digital
Signal Processing, Biological Signal Processing. Advising
undergraduate and graduate students (from the biomedical
and the hard sciences) on human neurophysiology and on
neuronal modeling and simulation. Coordinating many of the
activities of the lab. Research
Experience H-reflex, presynaptic and
reciprocal inhibition in humans, bilateral reflexes;
postural control; evoked brain potentials; human
electromyography; digital signal processing and
pattern recognition applied to neuroelectric signals;
modeling and simulation of neurons and neuronal
networks; biomedical instrumentation; crayfish
inhibitory synapse and stretch receptor dynamics.
pictures taken from
our neurophysiology lab Miscellany Recipient of the Ralph Crump
Award for Excellence in Medical Engineering at
UCLA in 1980. Member of the CNPq
(Brazilian N.S.F.) National Committee for Electrical and
Biomedical Engineering from 1991 to 1993 and 2005 to 2007.
Member of Scientific Committees of national and
international Conferences on Biomedical Engineering and
Neuronal Modeling. Hobbies Eco-travel
to wonderful forests, mountains, waterfalls and
beaches in Brazil.
Watching/listening DVDs and CDs (pop/rock,
classical, jazz), reading books, barbecue activities. Address or
(a non-post office box address): Universidade
de São Paulo, or
if you come personally: room D2-09 of block D 
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Specific Research Interests
andfkohn@leb.usp.br
Universidade de São Paulo,
Escola Politécnica, PTC
Cx.P. 61548
CEP 05424-970, São Paulo, S.P., Brasil
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Escola Politécnica, PTC
Av. Prof. Luciano Gualberto, Trav 3, 158
CEP 05508-900, São Paulo, S.P., Brasil
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at the Electrical Engineering
Building
Av. Prof. Luciano Gualberto, trav. 3, 158.
Cidade Universitária - CEP 05586-0600
São Paulo, SP, Brasill